BDBM50536484 CHEMBL4540942

SMILES: CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cnc2ccccc2c1

InChI Key: InChIKey=JEEMABKPXFIZPQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536484 (CHEMBL4540942) Show SMILES CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C26H20N6/c1-16-20(9-10-23-21(16)7-5-11-27-23)17(2)32-15-30-25-26(32)31-24(14-29-25)19-12-18-6-3-4-8-22(18)28-13-19/h3-15,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair