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SMILES: C(c1ccc2ncccc2c1)n1cnc2ncc(nc12)-c1cn[nH]c1

InChI Key: InChIKey=RQGLRNSEBLKCOU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536488
PNG
(CHEMBL4556499)
Show SMILES C(c1ccc2ncccc2c1)n1cnc2ncc(nc12)-c1cn[nH]c1
Show InChI InChI=1S/C18H13N7/c1-2-13-6-12(3-4-15(13)19-5-1)10-25-11-21-17-18(25)24-16(9-20-17)14-7-22-23-8-14/h1-9,11H,10H2,(H,22,23)
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PC cid
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n/an/an/an/a 13n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair