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BDBM50536493 CHEMBL4558786

SMILES: CC(NC\N=C\c1cnn(C)c1)c1ccc2ncccc2c1

InChI Key: InChIKey=BJQQULXKQNBAGE-GIJQJNRQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536493   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536493
PNG
(CHEMBL4558786)
Show SMILES CC(NC\N=C\c1cnn(C)c1)c1ccc2ncccc2c1
Show InChI InChI=1S/C17H19N5/c1-13(20-12-18-9-14-10-21-22(2)11-14)15-5-6-17-16(8-15)4-3-7-19-17/h3-11,13,20H,12H2,1-2H3/b18-9+
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.5n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair