BDBM50536497 CHEMBL4560881

SMILES: CNC(=O)c1ccc(\C=N\CNC(C)c2ccc3ncccc3c2)cc1F

InChI Key: InChIKey=ZTKOKSZYTFCHJF-WYMPLXKRSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536497 (CHEMBL4560881) Show SMILES CNC(=O)c1ccc(\C=N\CNC(C)c2ccc3ncccc3c2)cc1F Show InChI InChI=1S/C21H21FN4O/c1-14(16-6-8-20-17(11-16)4-3-9-25-20)26-13-24-12-15-5-7-18(19(22)10-15)21(27)23-2/h3-12,14,26H,13H2,1-2H3,(H,23,27)/b24-12+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair