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SMILES: CCC(c1ccc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnn(C)c1

InChI Key: InChIKey=UFIPTQSDQJKOFD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536501   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536501
PNG
(CHEMBL4548105)
Show SMILES CCC(c1ccc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C21H18FN7/c1-3-18(15-6-7-16-14(19(15)22)5-4-8-23-16)29-12-25-20-21(29)27-17(10-24-20)13-9-26-28(2)11-13/h4-12,18H,3H2,1-2H3
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n/an/an/an/a 14n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair