BDBM50536513 CHEMBL4561132

SMILES: CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1ccccc1

InChI Key: InChIKey=HBFPTPFSHAGLLJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536513 (CHEMBL4561132) Show SMILES CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1ccccc1 Show InChI InChI=1S/C22H15F2N5/c1-13(19-16(23)10-17-15(20(19)24)8-5-9-25-17)29-12-27-21-22(29)28-18(11-26-21)14-6-3-2-4-7-14/h2-13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair