BindingDB logo
myBDB logout

BDBM50536522 CHEMBL4542192

SMILES: CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnn(C)c1

InChI Key: InChIKey=HNTKBDBAZHXSLC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536522   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536522
PNG
(CHEMBL4542192)
Show SMILES CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C20H15F2N7/c1-11(17-14(21)6-15-13(18(17)22)4-3-5-23-15)29-10-25-19-20(29)27-16(8-24-19)12-7-26-28(2)9-12/h3-11H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair