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BDBM50536529 CHEMBL4589643

SMILES: CC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1

InChI Key: InChIKey=GMFSKAXYGCVANE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536529   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536529
PNG
(CHEMBL4589643)
Show SMILES CC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1
Show InChI InChI=1S/C23H16F2N6O/c1-12(16-7-13-3-2-6-27-19(13)9-18(16)25)31-11-29-22-23(31)30-20(10-28-22)14-4-5-15(21(26)32)17(24)8-14/h2-12H,1H3,(H2,26,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
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AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.70n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair