BDBM50536530 CHEMBL4529060

SMILES: Nc1ccc(cc1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1

InChI Key: InChIKey=RUPSBOPSOUVELY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536530 (CHEMBL4529060) Show SMILES Nc1ccc(cc1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C21H16N6/c22-17-6-4-15(5-7-17)19-11-24-20-21(26-19)27(13-25-20)12-14-3-8-18-16(10-14)2-1-9-23-18/h1-11,13H,12,22H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair