BDBM50536531 CHEMBL4559359

SMILES: CC(NC\N=C\c1ccc(C(N)=O)c(F)c1)c1ccc2ncccc2c1

InChI Key: InChIKey=IERQRQDIOPASON-FOKLQQMPSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536531 (CHEMBL4559359) Show SMILES CC(NC\N=C\c1ccc(C(N)=O)c(F)c1)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H19FN4O/c1-13(15-5-7-19-16(10-15)3-2-8-24-19)25-12-23-11-14-4-6-17(20(22)26)18(21)9-14/h2-11,13,25H,12H2,1H3,(H2,22,26)/b23-11+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair