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SMILES: CCC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cn[nH]c1

InChI Key: InChIKey=KSSSAXASWYMYSX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536542   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536542
PNG
(CHEMBL4576153)
Show SMILES CCC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cn[nH]c1
Show InChI InChI=1S/C20H16FN7/c1-2-18(14-6-12-4-3-5-22-16(12)7-15(14)21)28-11-24-19-20(28)27-17(10-23-19)13-8-25-26-9-13/h3-11,18H,2H2,1H3,(H,25,26)
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PC cid
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Article
PubMed
n/an/an/an/a 8.70n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair