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BDBM50536547 CHEMBL4563384

SMILES: CCC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(=O)NC)c(F)c1

InChI Key: InChIKey=WIRPRDQJRMCBHH-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536547   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536547
PNG
(CHEMBL4563384)
Show SMILES CCC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(=O)NC)c(F)c1
Show InChI InChI=1S/C25H20F2N6O/c1-3-22(17-9-14-5-4-8-29-20(14)11-19(17)27)33-13-31-23-24(33)32-21(12-30-23)15-6-7-16(18(26)10-15)25(34)28-2/h4-13,22H,3H2,1-2H3,(H,28,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.40n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair