BDBM50537023 CHEMBL4542099
SMILES: Cl.Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCCNC(N)=N)C(O)=O
InChI Key: InChIKey=ARYBZHNTGZMQTD-CZQHAQTBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine transporter 1 (Homo sapiens (Human)) | BDBM50537023 (CHEMBL4542099) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sydney Curated by ChEMBL | Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el... | J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine transporter 2 (Homo sapiens (Human)) | BDBM50537023 (CHEMBL4542099) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sydney Curated by ChEMBL | Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el... | J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 | |||||||||||
More data for this Ligand-Target Pair |