BDBM50537083 CHEMBL4550976
SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O
InChI Key: InChIKey=CNZBEMAMJJVIBN-QEGGNFSNSA-N
Data: 4 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Melanocortin receptor 5 (Mus musculus (Mouse)) | BDBM50537083 (CHEMBL4550976) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Full agonist activity at mouse MC5R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cA... | J Med Chem 62: 2738-2749 (2019) Article DOI: 10.1021/acs.jmedchem.9b00053 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Mus musculus) | BDBM50537083 (CHEMBL4550976) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Agonist activity at mouse MC4R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cAMP as... | J Med Chem 62: 2738-2749 (2019) Article DOI: 10.1021/acs.jmedchem.9b00053 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Mus musculus) | BDBM50537083 (CHEMBL4550976) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cAMP as... | J Med Chem 62: 2738-2749 (2019) Article DOI: 10.1021/acs.jmedchem.9b00053 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 1 (Mus musculus) | BDBM50537083 (CHEMBL4550976) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Full agonist activity at mouse MC1R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cA... | J Med Chem 62: 2738-2749 (2019) Article DOI: 10.1021/acs.jmedchem.9b00053 | |||||||||||
More data for this Ligand-Target Pair |