null
SMILES: COc1cc(Nc2ccnc3ccc(cc23)C(C)(C)C)cc(OC)c1OC
InChI Key: InChIKey=FPWOHBGDJPLADA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase NLK (Homo sapiens (Human)) | BDBM50537132 (CHEMBL530635 | TCMDC-138886) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a |
Johann Wolfgang Goethe University Curated by ChEMBL | Assay Description Binding affinity to biotinylated full length human NLK expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ba... | J Med Chem 62: 2830-2836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01213 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-G-associated kinase (Homo sapiens (Human)) | BDBM50537132 (CHEMBL530635 | TCMDC-138886) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a |
Johann Wolfgang Goethe University Curated by ChEMBL | Assay Description Binding affinity to biotinylated human GAK (13 to 338 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent T... | J Med Chem 62: 2830-2836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01213 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-G-associated kinase (Homo sapiens (Human)) | BDBM50537132 (CHEMBL530635 | TCMDC-138886) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Atypical kinase COQ8A, mitochondrial (Homo sapiens (Human)) | BDBM50537132 (CHEMBL530635 | TCMDC-138886) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a |
Johann Wolfgang Goethe University Curated by ChEMBL | Assay Description Binding affinity to biotinylated full length human ADCK3 expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ... | J Med Chem 62: 2830-2836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01213 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM50537132 (CHEMBL530635 | TCMDC-138886) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a |
Johann Wolfgang Goethe University Curated by ChEMBL | Assay Description Binding affinity to biotinylated human RIPK2 (1 to 310 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent ... | J Med Chem 62: 2830-2836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01213 | |||||||||||
More data for this Ligand-Target Pair |