BDBM50537206 CHEMBL4483783

SMILES: CN1CCN(CC1)c1nc(N)nc(CC2CCCCC2)n1

InChI Key: InChIKey=XDVBCPKSVWBVSR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor (H3 and H4) (Homo sapiens (Human))	BDBM50537206 (CHEMBL4483783) Show SMILES CN1CCN(CC1)c1nc(N)nc(CC2CCCCC2)n1 Show InChI InChI=1S/C15H26N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h12H,2-11H2,1H3,(H2,16,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from recombinant human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2/Gbeta1gamma2				Bioorg Med Chem 27: 1254-1262 (2019) Article DOI: 10.1016/j.bmc.2019.02.020
					More data for this Ligand-Target Pair
Histamine receptor (H3 and H4) (Homo sapiens (Human))	BDBM50537206 (CHEMBL4483783) Show SMILES CN1CCN(CC1)c1nc(N)nc(CC2CCCCC2)n1 Show InChI InChI=1S/C15H26N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h12H,2-11H2,1H3,(H2,16,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at recombinant human H4 receptor expressed in CHOK1 cells co-expressing Galpha16/aequorin assessed as inhibition of histamine-ind...				Bioorg Med Chem 27: 1254-1262 (2019) Article DOI: 10.1016/j.bmc.2019.02.020
					More data for this Ligand-Target Pair