BDBM50538006 CHEMBL4649232
SMILES: CCNC(=O)Nc1cnnc(c1)-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(O)=O)cc1
InChI Key: InChIKey=OXNNEMDLTGEMOR-IBGZPJMESA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ITGAV/ITGB1 (Homo sapiens (Human)) | BDBM50538006 (CHEMBL4649232) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 0.166 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pliant Therapeutics Curated by ChEMBL | Assay Description Displacement of [3H] C8 from human integrin alphavbeta1 incubated for 6 hrs by competition binding assay | J Med Chem 63: 5675-5696 (2020) | |||||||||||
More data for this Ligand-Target Pair |