BDBM50538100 CHEMBL4648350
SMILES: CNCCc1c[nH]c2cccc(O)c12
InChI Key: InChIKey=MTJOWJUQGYWRHT-UHFFFAOYSA-N
Data: 4 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50538100 (CHEMBL4648350) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by... | J Nat Prod 83: 461-467 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50538100 (CHEMBL4648350) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by... | J Nat Prod 83: 461-467 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50538100 (CHEMBL4648350) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by... | J Nat Prod 83: 461-467 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50538100 (CHEMBL4648350) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by... | J Nat Prod 83: 461-467 (2020) | |||||||||||
More data for this Ligand-Target Pair |