BDBM50538167 CHEMBL4632813

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(NC(=O)CN2CCOCC2)cc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(C)=O)C(=O)[C@@]1(C)CO1

InChI Key: InChIKey=YFIDNTNWKHGBCQ-CLFOAKAGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-9 (Homo sapiens (Human))	BDBM50538167 (CHEMBL4632813) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(NC(=O)CN2CCOCC2)cc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(C)=O)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C33H48N6O8/c1-21(2)16-25(30(43)33(4)20-47-33)36-31(44)26(37-32(45)27-6-5-11-39(27)29(42)18-34-22(3)40)17-23-7-9-24(10-8-23)35-28(41)19-38-12-14-46-15-13-38/h7-10,21,25-27H,5-6,11-20H2,1-4H3,(H,34,40)(H,35,41)(H,36,44)(H,37,45)/t25-,26-,27-,33+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysis				J Med Chem 63: 3763-3783 (2020)
					More data for this Ligand-Target Pair