BDBM50538372 CHEMBL4637262

SMILES: CC(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key: InChIKey=GUJNVPQGUFMHQI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538372 (CHEMBL4637262) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H29N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-10-11-28-15-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-9,12-14,17,28H,10-11,15-16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020)
					More data for this Ligand-Target Pair
Glucose transporter (Homo sapiens (Human))	BDBM50538372 (CHEMBL4637262) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H29N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-10-11-28-15-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-9,12-14,17,28H,10-11,15-16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020)
					More data for this Ligand-Target Pair