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SMILES: N[C@]1(C[C@]2(CCNC2)C[C@@H]1CCCB(O)O)C(O)=O

InChI Key: InChIKey=QZLUPYXYXWEXHN-DLOVCJGASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538523   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arginase-1


(Homo sapiens (Human))		BDBM50538523
PNG
(CHEMBL4646013)
Show SMILES N[C@]1(C[C@]2(CCNC2)C[C@@H]1CCCB(O)O)C(O)=O |r|
Show InChI InChI=1S/C12H23BN2O4/c14-12(10(16)17)7-11(3-5-15-8-11)6-9(12)2-1-4-13(18)19/h9,15,18-19H,1-8,14H2,(H,16,17)/t9-,11-,12-/m0/s1
PDB
MMDB

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PC cid
PC sid
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n/an/a 13n/an/an/an/an/an/a



Merck & Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assay

ACS Med Chem Lett 11: 582-588 (2020)

More data for this
Ligand-Target Pair