BDBM50538577 CHEMBL4648623

SMILES: C[C@H]1NCCO[C@@H]1Cc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4CC4C3=O)sc12

InChI Key: InChIKey=QANIPMSZUGTHAV-IHDNSLFNSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50538577 (CHEMBL4648623) Show SMILES C[C@H]1NCCO[C@@H]1Cc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4CC4C3=O)sc12 |r| Show InChI InChI=1S/C26H26ClN3O3S/c1-13-7-15(27)8-19(18(13)11-23-14(2)28-5-6-33-23)17-3-4-29-22-9-16(34-24(17)22)12-30-25(31)20-10-21(20)26(30)32/h3-4,7-9,14,20-21,23,28H,5-6,10-12H2,1-2H3/t14-,20?,21?,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...				J Med Chem 63: 5398-5420 (2020)
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50538577 (CHEMBL4648623) Show SMILES C[C@H]1NCCO[C@@H]1Cc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4CC4C3=O)sc12 |r| Show InChI InChI=1S/C26H26ClN3O3S/c1-13-7-15(27)8-19(18(13)11-23-14(2)28-5-6-33-23)17-3-4-29-22-9-16(34-24(17)22)12-30-25(31)20-10-21(20)26(30)32/h3-4,7-9,14,20-21,23,28H,5-6,10-12H2,1-2H3/t14-,20?,21?,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant full length USP7 (unknown origin) using ubiquintin-rhodamine as substrate preincubated for 30 mins followed by substrate ad...				J Med Chem 63: 5398-5420 (2020)
					More data for this Ligand-Target Pair