BDBM50539492 CHEMBL4634284

SMILES: CC(C)(C)CNCCc1c[nH]c2c1C(=O)C(=CC2=O)c1cccnc1

InChI Key: InChIKey=VEOLSQVPTKSVQG-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50539492 (CHEMBL4634284) Show SMILES CC(C)(C)CNCCc1c[nH]c2c1C(=O)C(=CC2=O)c1cccnc1 |c:16| Show InChI InChI=1S/C20H23N3O2/c1-20(2,3)12-22-8-6-14-11-23-18-16(24)9-15(19(25)17(14)18)13-5-4-7-21-10-13/h4-5,7,9-11,22-23H,6,8,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	4.53E+3	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated IDO1 in human HeLa cells				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50539492 (CHEMBL4634284) Show SMILES CC(C)(C)CNCCc1c[nH]c2c1C(=O)C(=CC2=O)c1cccnc1 |c:16| Show InChI InChI=1S/C20H23N3O2/c1-20(2,3)12-22-8-6-14-11-23-18-16(24)9-15(19(25)17(14)18)13-5-4-7-21-10-13/h4-5,7,9-11,22-23H,6,8,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair