BDBM50539553 CHEMBL4644995
SMILES: CCn1nnc2c(C)c(ccc12)[C@@H]([C@H](C)C(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1c(C)c(C)cc(C)c1C
InChI Key: InChIKey=JUBFIKLKLFGJNP-JHOBJCJYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human)) | BDBM50539553 (CHEMBL4644995) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Biogen Curated by ChEMBL | Assay Description Induction of Nrf2 nuclear translocation in human U2OS cells | Bioorg Med Chem Lett 30: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
KEAP1/Cullin-3/Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM50539553 (CHEMBL4644995) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a |
Biogen Curated by ChEMBL | Assay Description Binding affinity to Keap1 (unknown origin) by SPR assay | Bioorg Med Chem Lett 30: (2020) | |||||||||||
More data for this Ligand-Target Pair |