BDBM50539966 CHEMBL4634547

SMILES: CN[C@H]1CCN(C[C@@H]1F)c1nc(N(C)CCC#N)c2sccc2n1

InChI Key: InChIKey=HMVNYEPSKJGOHX-RYUDHWBXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide N-myristoyltransferase (Homo sapiens (Human))	BDBM50539966 (CHEMBL4634547) Show SMILES CN[C@H]1CCN(C[C@@H]1F)c1nc(N(C)CCC#N)c2sccc2n1 |r| Show InChI InChI=1S/C16H21FN6S/c1-19-12-4-8-23(10-11(12)17)16-20-13-5-9-24-14(13)15(21-16)22(2)7-3-6-18/h5,9,11-12,19H,3-4,7-8,10H2,1-2H3/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of human NMT1 using p60 SRC(2 to 16) as substrate by CPM dye based fluorescence assay				J Med Chem 63: 7740-7765 (2020)
					More data for this Ligand-Target Pair