BDBM50540038 CHEMBL4642557

SMILES: CC(C)n1ncc2c1nc(N[C@H](C)c1ccc(Cl)cc1)n(C)c2=O

InChI Key: InChIKey=WGNYQVZFDDKWFR-LLVKDONJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM50540038 (CHEMBL4642557) Show SMILES CC(C)n1ncc2c1nc(N[C@H](C)c1ccc(Cl)cc1)n(C)c2=O |r| Show InChI InChI=1S/C17H20ClN5O/c1-10(2)23-15-14(9-19-23)16(24)22(4)17(21-15)20-11(3)12-5-7-13(18)8-6-12/h5-11H,1-4H3,(H,20,21)/t11-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting method				J Med Chem 63: 7867-7879 (2020)
					More data for this Ligand-Target Pair