BDBM50540053 CHEMBL4633871

SMILES: Clc1ccc(Cl)c(c1)-c1cc(\C=C(/C#N)C(=O)Nc2cccc3ncccc23)co1

InChI Key: InChIKey=IVECIQOGZAMPGO-OQLLNIDSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50540053 (CHEMBL4633871) Show SMILES Clc1ccc(Cl)c(c1)-c1cc(\C=C(/C#N)C(=O)Nc2cccc3ncccc23)co1 Show InChI InChI=1S/C23H13Cl2N3O2/c24-16-6-7-19(25)18(11-16)22-10-14(13-30-22)9-15(12-26)23(29)28-21-5-1-4-20-17(21)3-2-8-27-20/h1-11,13H,(H,28,29)/b15-9+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of sirtuin 2 (unknown origin)				Eur J Med Chem 161: 48-77 (2019)
					More data for this Ligand-Target Pair