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SMILES: COC(=O)CN1C(=O)N(CCCCN2CCN(CC2)c2ccccc2OC)C(C1=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=LUIJLIIDIVJXQI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540075   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosinase


(Homo sapiens (Human))		BDBM50540075
PNG
(CHEMBL2078992)
Show SMILES COC(=O)CN1C(=O)N(CCCCN2CCN(CC2)c2ccccc2OC)C(C1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H38N4O5/c1-41-29-18-10-9-17-28(29)35-23-21-34(22-24-35)19-11-12-20-37-32(40)36(25-30(38)42-2)31(39)33(37,26-13-5-3-6-14-26)27-15-7-4-8-16-27/h3-10,13-18H,11-12,19-25H2,1-2H3
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
PubMed
n/an/a 1.07E+3n/an/an/an/an/an/a



College of Pharmacy and Gachon Institute of Pharmaceutical Science

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin)

Eur J Med Chem 164: 517-545 (2019)

More data for this
Ligand-Target Pair