BDBM50540317 CHEMBL4635775

SMILES: CC(O)c1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CCC3)c12

InChI Key: InChIKey=FSNBHIJYWMXLPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50540317 (CHEMBL4635775) Show SMILES CC(O)c1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CCC3)c12 Show InChI InChI=1S/C21H23N7O/c1-13(29)14-5-7-15(8-6-14)19-16(11-24-26(19)2)18-17-20(27(3)25-18)22-12-23-21(17)28-9-4-10-28/h5-8,11-13,29H,4,9-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 (unknown origin)				J Med Chem 63: 6387-6406 (2020)
					More data for this Ligand-Target Pair