BDBM50541033 GEMICHALCONE A::Gemichalcone A

SMILES: COc1cc(\C=C\C(=O)OC\C(C)=C/Cc2c(O)ccc(C(=O)\C=C\c3ccc(O)cc3)c2O)ccc1O

InChI Key: InChIKey=OZHIKCIPCFAOPM-MZNNUVDVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (Rattus norvegicus)	BDBM50541033 (GEMICHALCONE A | Gemichalcone A) Show SMILES COc1cc(\C=C\C(=O)OC\C(C)=C/Cc2c(O)ccc(C(=O)\C=C\c3ccc(O)cc3)c2O)ccc1O Show InChI InChI=1S/C30H28O8/c1-19(18-38-29(35)16-8-21-7-14-27(34)28(17-21)37-2)3-11-23-26(33)15-12-24(30(23)36)25(32)13-6-20-4-9-22(31)10-5-20/h3-10,12-17,31,33-34,36H,11,18H2,1-2H3/b13-6+,16-8+,19-3-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of degranulated rat peritoneal mast cells beta-glucuronidase				Eur J Med Chem 187: (2020)
					More data for this Ligand-Target Pair
Beta-glucuronidase (Rattus norvegicus)	BDBM50541033 (GEMICHALCONE A | Gemichalcone A) Show SMILES COc1cc(\C=C\C(=O)OC\C(C)=C/Cc2c(O)ccc(C(=O)\C=C\c3ccc(O)cc3)c2O)ccc1O Show InChI InChI=1S/C30H28O8/c1-19(18-38-29(35)16-8-21-7-14-27(34)28(17-21)37-2)3-11-23-26(33)15-12-24(30(23)36)25(32)13-6-20-4-9-22(31)10-5-20/h3-10,12-17,31,33-34,36H,11,18H2,1-2H3/b13-6+,16-8+,19-3-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of degranulated rat neutrophils beta-glucuronidase				Eur J Med Chem 187: (2020)
					More data for this Ligand-Target Pair