BDBM50541407 CHEMBL4638635

SMILES: Cc1cccc(c1)[C@H]1CC[C@H](N1C(=O)CNC(=O)c1ccc(Cc2cc(C)n[nH]c2=O)c(C)c1)C(C)(C)C#N

InChI Key: InChIKey=LHCOLCAUMRHKNE-SXOMAYOGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50541407 (CHEMBL4638635) Show SMILES Cc1cccc(c1)[C@H]1CC[C@H](N1C(=O)CNC(=O)c1ccc(Cc2cc(C)n[nH]c2=O)c(C)c1)C(C)(C)C#N |r| Show InChI InChI=1S/C31H35N5O3/c1-19-7-6-8-23(13-19)26-11-12-27(31(4,5)18-32)36(26)28(37)17-33-29(38)24-10-9-22(20(2)14-24)16-25-15-21(3)34-35-30(25)39/h6-10,13-15,26-27H,11-12,16-17H2,1-5H3,(H,33,38)(H,35,39)/t26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biohaven Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human CLR/RAMP1				J Med Chem 63: 6600-6623 (2020)
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