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SMILES: Cc1cc(Oc2c(C)cc(cc2F)C(=O)N[C@H]2C[C@]3(CC[C@@H](N3C2=O)C(C)(C)C#N)c2ccc(F)cc2C)c(=O)[nH]n1

InChI Key: InChIKey=AMDUPVQLAGRNKD-XXYDJGGASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541408   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1


(Homo sapiens (Human))		BDBM50541408
PNG
(CHEMBL4643140)
Show SMILES Cc1cc(Oc2c(C)cc(cc2F)C(=O)N[C@H]2C[C@]3(CC[C@@H](N3C2=O)C(C)(C)C#N)c2ccc(F)cc2C)c(=O)[nH]n1 |r|
Show InChI InChI=1S/C31H31F2N5O4/c1-16-11-20(32)6-7-21(16)31-9-8-25(30(4,5)15-34)38(31)29(41)23(14-31)35-27(39)19-10-17(2)26(22(33)13-19)42-24-12-18(3)36-37-28(24)40/h6-7,10-13,23,25H,8-9,14H2,1-5H3,(H,35,39)(H,37,40)/t23-,25+,31+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
 0.00400n/an/an/an/an/an/an/an/a



Biohaven Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CLR/RAMP1

J Med Chem 63: 6600-6623 (2020)

More data for this
Ligand-Target Pair