BDBM50541998 CHEMBL4642592
SMILES: CC(=O)N1CCC(CC1)c1ccc(cc1)-c1cc(cc2cc(ccc12)-c1ccc(cc1)C(F)(F)F)C(O)=O
InChI Key: InChIKey=AFRXCTUPOJKNDG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Translocator protein (Homo sapiens (Human)) | BDBM50541998 (CHEMBL4642592) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to TSPO receptor (unknown origin) | J Med Chem 63: 9563-9589 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50541998 (CHEMBL4642592) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to 5HT1D receptor (unknown origin) | J Med Chem 63: 9563-9589 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50541998 (CHEMBL4642592) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 4.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to DRD3 (unknown origin) | J Med Chem 63: 9563-9589 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50541998 (CHEMBL4642592) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 4.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to dopamine D5 receptor (unknown origin) | J Med Chem 63: 9563-9589 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y14 (Homo sapiens (Human)) | BDBM50541998 (CHEMBL4642592) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Saint Louis University School of Medicine Curated by ChEMBL | Assay Description Displacement of Alexafluor488 labeled 4-(4-(1-(4-(1-(6-(4-(6-amino-3-imino-4,5-disulfo-3H-xanthen-9-yl)-3-carboxybenzamido)hexyl)-1H-1,2,3-triazol-4-... | ACS Med Chem Lett 11: 1281-1286 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50541998 (CHEMBL4642592) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of MRS4174 binding to mouse P2Y14R expressed in HEK293 cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 3... | J Med Chem 63: 9563-9589 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50541998 (CHEMBL4642592) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Saint Louis University School of Medicine Curated by ChEMBL | Assay Description Displacement of Alexafluor488 labeled 4-(4-(1-(4-(1-(6-(4-(6-amino-3-imino-4,5-disulfo-3H-xanthen-9-yl)-3-carboxybenzamido)hexyl)-1H-1,2,3-triazol-4-... | ACS Med Chem Lett 11: 1281-1286 (2020) | |||||||||||
More data for this Ligand-Target Pair |