BDBM50542112 CHEMBL4638383

SMILES: Nc1ccc(cc1)-c1cncc2ccc(OC[C@@H]3CCCN3)cc12

InChI Key: InChIKey=AYMMPPYKBCPEKZ-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C iota type/zeta type (Homo sapiens (Human))	BDBM50542112 (CHEMBL4638383) Show SMILES Nc1ccc(cc1)-c1cncc2ccc(OC[C@@H]3CCCN3)cc12 |r| Show InChI InChI=1S/C20H21N3O/c21-16-6-3-14(4-7-16)20-12-22-11-15-5-8-18(10-19(15)20)24-13-17-2-1-9-23-17/h3-8,10-12,17,23H,1-2,9,13,21H2/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method				J Med Chem 63: 7143-7162 (2020)
					More data for this Ligand-Target Pair