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BDBM50542141 CHEMBL4642360

SMILES: ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC(=C)C[C@H]1C(=O)Nc1ccc(F)cn1

InChI Key: InChIKey=FGYHGBGJGOUSBC-WBVHZDCISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542141   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase mitochondrial


(Homo sapiens (Human))		BDBM50542141
PNG
(CHEMBL4642360)
Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC(=C)C[C@H]1C(=O)Nc1ccc(F)cn1 |r|
Show InChI InChI=1S/C21H27FN4O4/c1-13-8-17(20(28)24-18-7-6-16(22)11-23-18)26(12-13)21(29)15(10-19(27)25-30)9-14-4-2-3-5-14/h6-7,11,14-15,17,30H,1-5,8-10,12H2,(H,25,27)(H,23,24,28)/t15-,17+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
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AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 7.20n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...

J Med Chem 63: 6959-6978 (2020)

More data for this
Ligand-Target Pair