BDBM50542151 CHEMBL4635093

SMILES: ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cc1C(F)(F)F

InChI Key: InChIKey=VGLUKVYWZIAUNH-BEFAXECRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide deformylase mitochondrial (Homo sapiens (Human))	BDBM50542151 (CHEMBL4635093) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C24H29F4N3O4/c25-16-5-6-18(17(11-16)24(26,27)28)29-21(33)19-12-23(7-8-23)13-31(19)22(34)15(10-20(32)30-35)9-14-3-1-2-4-14/h5-6,11,14-15,19,35H,1-4,7-10,12-13H2,(H,29,33)(H,30,32)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020)
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