BDBM50542152 CHEMBL4641062

SMILES: ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccccc1

InChI Key: InChIKey=OVNOAUWBQFKVEC-MOPGFXCFSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide deformylase mitochondrial (Homo sapiens (Human))	BDBM50542152 (CHEMBL4641062) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccccc1 |r| Show InChI InChI=1S/C24H30N4O4/c29-20(26-31)13-18(12-16-6-4-5-7-16)23(30)28-15-24(10-11-24)14-19(28)22-25-21(27-32-22)17-8-2-1-3-9-17/h1-3,8-9,16,18-19,31H,4-7,10-15H2,(H,26,29)/t18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50542152 (CHEMBL4641062) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccccc1 |r| Show InChI InChI=1S/C24H30N4O4/c29-20(26-31)13-18(12-16-6-4-5-7-16)23(30)28-15-24(10-11-24)14-19(28)22-25-21(27-32-22)17-8-2-1-3-9-17/h1-3,8-9,16,18-19,31H,4-7,10-15H2,(H,26,29)/t18-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50542152 (CHEMBL4641062) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccccc1 |r| Show InChI InChI=1S/C24H30N4O4/c29-20(26-31)13-18(12-16-6-4-5-7-16)23(30)28-15-24(10-11-24)14-19(28)22-25-21(27-32-22)17-8-2-1-3-9-17/h1-3,8-9,16,18-19,31H,4-7,10-15H2,(H,26,29)/t18-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair