BDBM50542164 CHEMBL4635911

SMILES: ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cc1C(F)(F)F

InChI Key: InChIKey=QJELKHPYTGUQHI-BEFAXECRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide deformylase mitochondrial (Homo sapiens (Human))	BDBM50542164 (CHEMBL4635911) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C25H28F4N4O4/c26-16-5-6-17(18(11-16)25(27,28)29)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50542164 (CHEMBL4635911) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C25H28F4N4O4/c26-16-5-6-17(18(11-16)25(27,28)29)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50542164 (CHEMBL4635911) Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1c1nc(no1)-c1ccc(F)cc1C(F)(F)F |r| Show InChI InChI=1S/C25H28F4N4O4/c26-16-5-6-17(18(11-16)25(27,28)29)21-30-22(37-32-21)19-12-24(7-8-24)13-33(19)23(35)15(10-20(34)31-36)9-14-3-1-2-4-14/h5-6,11,14-15,19,36H,1-4,7-10,12-13H2,(H,31,34)/t15-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020)
					More data for this Ligand-Target Pair