BDBM50542435 CHEMBL4642218

SMILES: Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)\C=C\c1ccc(F)cc1

InChI Key: InChIKey=ZXXQYHUKPNBJPO-DTQAZKPQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50542435 (CHEMBL4642218) Show SMILES Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C25H18FNO/c1-17-24(23(28)16-13-18-11-14-20(26)15-12-18)25(19-7-3-2-4-8-19)21-9-5-6-10-22(21)27-17/h2-16H,1H3/b16-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
China-Japan Union Hospital of Jilin University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by ELISA				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50542435 (CHEMBL4642218) Show SMILES Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C25H18FNO/c1-17-24(23(28)16-13-18-11-14-20(26)15-12-18)25(19-7-3-2-4-8-19)21-9-5-6-10-22(21)27-17/h2-16H,1H3/b16-13+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
China-Japan Union Hospital of Jilin University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by ELISA				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair