BDBM50542646 CHEMBL4648807

SMILES: FCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12

InChI Key: InChIKey=UHCLWDTUJJRZCA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542646 (CHEMBL4648807) Show SMILES FCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H22FN5O/c22-7-1-2-10-25-17(11-15-12-23-8-5-18(15)25)14-26-20-13-24-9-6-19(20)27(21(26)28)16-3-4-16/h5-6,8-9,11-13,16H,1-4,7,10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair