BDBM50542647 CHEMBL4644338

SMILES: FC(F)(F)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12

InChI Key: InChIKey=ZHFKSLVRVDLBKO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542647 (CHEMBL4644338) Show SMILES FC(F)(F)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H20F3N5O/c22-21(23,24)6-1-9-27-16(10-14-11-25-7-4-17(14)27)13-28-19-12-26-8-5-18(19)29(20(28)30)15-2-3-15/h4-5,7-8,10-12,15H,1-3,6,9,13H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.251	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair