BDBM50542651 CHEMBL4636246

SMILES: CC1(CC1)n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCS(C)(=O)=O)c1=O

InChI Key: InChIKey=RYZZBCKKEWOPLO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542651 (CHEMBL4636246) Show SMILES CC1(CC1)n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCS(C)(=O)=O)c1=O Show InChI InChI=1S/C23H25ClN4O3S/c1-23(7-8-23)28-20-6-9-25-14-21(20)27(22(28)29)15-18-13-16-12-17(24)4-5-19(16)26(18)10-3-11-32(2,30)31/h4-6,9,12-14H,3,7-8,10-11,15H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair