BDBM50542656 CHEMBL4648250

SMILES: CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CN(C3)S(C)(=O)=O)c2=O)cc2cc(Cl)ccc12

InChI Key: InChIKey=ATJVTFOLWQWDLN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542656 (CHEMBL4648250) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CN(C3)S(C)(=O)=O)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C23H26ClN5O5S2/c1-35(31,32)9-3-8-27-18(11-16-10-17(24)4-5-20(16)27)15-28-22-12-25-7-6-21(22)29(23(28)30)19-13-26(14-19)36(2,33)34/h4-7,10-12,19H,3,8-9,13-15H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair