BDBM50543572 CHEMBL4641639

SMILES: COC(=O)c1ccc2\C(=C(\Nc3ccc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key: InChIKey=HDMDHLQOFWCVOU-MVJHLKBCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VHL/PDGFRB (Homo sapiens (Human))	BDBM50543572 (CHEMBL4641639) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C34H35N5O3/c1-23-20-26(12-14-30(23)39-15-7-10-27(39)22-38-18-16-37(2)17-19-38)35-32(24-8-5-4-6-9-24)31-28-13-11-25(34(41)42-3)21-29(28)36-33(31)40/h4-15,20-21,35H,16-19,22H2,1-3H3,(H,36,40)/b32-31-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50543572 (CHEMBL4641639) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C34H35N5O3/c1-23-20-26(12-14-30(23)39-15-7-10-27(39)22-38-18-16-37(2)17-19-38)35-32(24-8-5-4-6-9-24)31-28-13-11-25(34(41)42-3)21-29(28)36-33(31)40/h4-15,20-21,35H,16-19,22H2,1-3H3,(H,36,40)/b32-31-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST fused human VEGFR2 cytoplasmic domain (790 to 1356 (end) residues) expressed in baculovirus expression system using FAM-...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair