BDBM50543576 CHEMBL4641415

SMILES: COC(=O)c1ccc2\C(=C(\Nc3cnc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key: InChIKey=QIZVZLQPDQCTMR-FLWNBWAVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VHL/PDGFRB (Homo sapiens (Human))	BDBM50543576 (CHEMBL4641415) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3cnc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C33H34N6O3/c1-22-18-25(20-34-31(22)39-13-7-10-26(39)21-38-16-14-37(2)15-17-38)35-30(23-8-5-4-6-9-23)29-27-12-11-24(33(41)42-3)19-28(27)36-32(29)40/h4-13,18-20,35H,14-17,21H2,1-3H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50543576 (CHEMBL4641415) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3cnc(c(C)c3)-n3cccc3CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C33H34N6O3/c1-22-18-25(20-34-31(22)39-13-7-10-26(39)21-38-16-14-37(2)15-17-38)35-30(23-8-5-4-6-9-23)29-27-12-11-24(33(41)42-3)19-28(27)36-32(29)40/h4-13,18-20,35H,14-17,21H2,1-3H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST fused human VEGFR2 cytoplasmic domain (790 to 1356 (end) residues) expressed in baculovirus expression system using FAM-...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair