BDBM50543787 CHEMBL4645582

SMILES: C[C@@H](Oc1cncc(c1)-c1cnn(c1)C1CCN(CC(N)=O)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=SFQMXFAAJRZASN-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50543787 (CHEMBL4645582) Show SMILES C[C@@H](Oc1cncc(c1)-c1cnn(c1)C1CCN(CC(N)=O)CC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C23H24Cl2FN5O2/c1-14(22-19(24)2-3-20(26)23(22)25)33-18-8-15(9-28-11-18)16-10-29-31(12-16)17-4-6-30(7-5-17)13-21(27)32/h2-3,8-12,14,17H,4-7,13H2,1H3,(H2,27,32)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by ADP-Glo kinase assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair