BDBM50544036 CHEMBL4634194

SMILES: CN1CCN(CC1)c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key: InChIKey=OFKXWUKNKVGNPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sirtuin-6 (SIRT6) (Homo sapiens (Human))	BDBM50544036 (CHEMBL4634194) Show SMILES CN1CCN(CC1)c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C12H14F3N3O2/c1-16-4-6-17(7-5-16)9-2-3-11(18(19)20)10(8-9)12(13,14)15/h2-3,8H,4-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair