BDBM50544262 CHEMBL4647093

SMILES: CCN(CC)CCNc1ccc2c(c1)nc1\C(CCn1c2=O)=C\c1ccc(cc1)C(C)C

InChI Key: InChIKey=SUPBKGUCTOYDLR-OQKWZONESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50544262 (CHEMBL4647093) Show SMILES CCN(CC)CCNc1ccc2c(c1)nc1\C(CCn1c2=O)=C\c1ccc(cc1)C(C)C Show InChI InChI=1S/C27H34N4O/c1-5-30(6-2)16-14-28-23-11-12-24-25(18-23)29-26-22(13-15-31(26)27(24)32)17-20-7-9-21(10-8-20)19(3)4/h7-12,17-19,28H,5-6,13-16H2,1-4H3/b22-17+	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwi...				J Med Chem 63: 9752-9772 (2020)
					More data for this Ligand-Target Pair