BDBM50544285 CHEMBL4633150

SMILES: CCN(CC)CCCNc1cc2nc(\C=C\c3ccc(CC(C)C)cc3)[nH]c(=O)c2cc1F

InChI Key: InChIKey=SJXGAVXKBOTKAL-OUKQBFOZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50544285 (CHEMBL4633150) Show SMILES CCN(CC)CCCNc1cc2nc(\C=C\c3ccc(CC(C)C)cc3)[nH]c(=O)c2cc1F Show InChI InChI=1S/C27H35FN4O/c1-5-32(6-2)15-7-14-29-25-18-24-22(17-23(25)28)27(33)31-26(30-24)13-12-20-8-10-21(11-9-20)16-19(3)4/h8-13,17-19,29H,5-7,14-16H2,1-4H3,(H,30,31,33)/b13-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwi...				J Med Chem 63: 9752-9772 (2020)
					More data for this Ligand-Target Pair