BDBM50544636 CHEMBL4632867

SMILES: C[C@@]1(O)[C@H](F)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1cnc2c1nc(N)[nH]c2=O

InChI Key: InChIKey=KECIPRYXBUARHA-GITKWUPZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50544636 (CHEMBL4632867) Show SMILES C[C@@]1(O)[C@H](F)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1cnc2c1nc(N)[nH]c2=O |r| Show InChI InChI=1S/C11H17FN5O13P3/c1-11(19)6(12)4(2-27-32(23,24)30-33(25,26)29-31(20,21)22)28-9(11)17-3-14-5-7(17)15-10(13)16-8(5)18/h3-4,6,9,19H,2H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,18)/t4-,6-,9-,11-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Janssen BioPharma, Inc. Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into R...				J Med Chem 63: 10380-10395 (2020)
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